Machado was dealing with low-back tightness and shoulder discomfort in the ninth inning of Friday's loss to the Dodgers, Bill Shaikin of the Los Angeles Times reports.
Machado went 1-for-3 with a two-run home run and another RBI during Thursday's win over the Pirates.
Stammen earned the save Thursday after holding the Pirates scoreless across three innings, allowing three hits and no walks while striking out two.
Paddack (1-1) earned the win Thursday after holding the Pirates to three runs (one earned) on five hits and a pair of walks while striking out four across five innings.
Tatis (shoulder) is expected to be reinstated from the 10-day injured list Friday, Dennis Lin of The Athletic reports.
Lamet is slated to throw a 70-pitch simulated game at the Padres' alternate training site Thursday, the Associated Press reports.
Myers (patellar tendinitis) is not in Thursday's lineup against the Pirates.
Musgrove (2-1) allowed one run on four hits and two walks while striking out six batters in a loss to the Pirates on Wednesday.
Pham went 1-for-3 with a walk, an RBI and a stolen base in Wednesday's 5-1 loss to the Pirates.
Altavilla (calf) was reinstated from the 10-day injured list Wednesday.
Williams was placed on the 10-day injured list Wednesday with right knee inflammation.
Crismatt was optioned to the alternate training site Wednesday.
Johnson (groin) was reinstated from the injured list prior to Wednesday's game against the Pirates.
Johnson (groin) will likely be activated from the 10-day injured list Wednesday, Kevin Acee of The San Diego Union-Tribune reports.
Myers has been dealing with patellar tendinitis recently but could be available off the bench Wednesday, Dennis Lin of The Athletic reports.
Myers (knee) isn't starting Wednesday's game against the Pirates.
Crismatt (0-1) suffered the first loss of his career Tuesday against the Pirates as he allowed four runs (three earned) on eight hits while striking out five over five innings.
Snell allowed three runs on three hits and two walks while striking out a batter in just two-thirds of an inning against Pittsburgh on Tuesday and did not factor in the decision.
Myers (knee) was removed from Tuesday's game against the Pirates with right knee inflammation, AJ Cassavell of MLB.com reports.
Myers was removed from Wednesday's game at Pittsburgh with an apparent injury, Kevin Acee of The San Diego Union-Tribune reports.
Kim is out of the lineup for Tuesday's game against the Pirates.
Caratini is out of the lineup for Tuesday's game against the Pirates.
Darvish (1-0) allowed one run on three hits and a walk over seven innings Monday, striking out six and picking up a won over the Pirates.
Machado went 1-for-4 with a walk, a stolen base and two runs scored in Monday's 6-2 win over the Pirates.
Myers went 3-for-5 with a homer and five RBI in Monday's 6-2 win over Pittsburgh.