McCaffrey agreed to terms Monday with the Panthers on a four-year, $64 million contract, Adam Schefter of ESPN reports.
McCaffrey ran for 26 yards and a touchdown on nine carries and caught seven of 10 targets for 72 receiving yards during Sunday's 42-10 loss to the Saints.
McCaffrey ran for 54 yards on 13 carries and added 15 catches on 15 targets for 119 yards during Sunday's 38-6 loss to the Colts.
McCaffrey carried 19 times for 87 yards and two touchdowns Sunday against the Seahawks. He also caught eight of 10 targets for 88 yards in the 30-24 loss.
McCaffrey ran for 53 yards on 11 carries and caught 11 of 12 targets for 82 receiving yards during Sunday's 40-20 loss to Atlanta.
McCaffrey carried 14 times for 44 yards and caught seven of 13 targets for 58 additional yards during Sunday's 29-21 loss to the Redskins.
McCaffrey rushed 22 times for 64 yards and a touchdown while catching all nine of his targets for 69 yards and a touchdown in Sunday's 34-31 loss to the Saints.
McCaffrey tallied 70 rushing yards on 14 carries and caught 11 of 14 targets for 121 receiving yards during Sunday's 29-3 loss to the Falcons.
McCaffrey (foot) practiced fully Thursday, Brendan Marks of The Charlotte Observer reports.
McCaffrey didn't practice Wednesday due to a foot injury, Steve Reed of the Associated Press reports.