San Francisco 49ers
VS.
San Francisco 49ers
STAT RANK
| Week # | Date | Opponent | Results | Record | Streak | |
|---|---|---|---|---|---|---|
| 1 | Sunday, Sep. 7 |
@
Sea
|
W 17-13 | 1-0-0 | Won 1 | Boxscore |
| 2 | Sunday, Sep. 14 |
@
NO
|
W 26-21 | 2-0-0 | Won 2 | Boxscore |
| 3 | Sunday, Sep. 21 |
vs
Ari
|
W 16-15 | 3-0-0 | Won 3 | Boxscore |
| 4 | Sunday, Sep. 28 |
vs
Jax
|
L 26-21 | 3-1-0 | Lost 1 | Boxscore |
| 5 | Thursday, Oct. 2 |
@
LAR
|
W 26-23 | 4-1-0 | Won 1 | Boxscore |
| 6 | Sunday, Oct. 12 |
@
TB
|
L 30-19 | 4-2-0 | Lost 1 | Boxscore |
| 7 | Sunday, Oct. 19 |
vs
Atl
|
W 20-10 | 5-2-0 | Won 1 | Boxscore |
October 20, 2025
| Malik Turner (WR) | Reverted back to the San Francisco 49ers practice squad. |
| Nick Zakelj (OG/C) | Reverted back to the San Francisco 49ers practice squad. |
October 18, 2025
| Brayden Willis (TE) | Waived by the San Francisco 49ers. |
| Fred Warner (LB) | Ankle fracture, injured reserve. |
| George Kittle (TE) | Activated from injured reserve. |
| Kevin Givens (DT) | Activated from injured reserve. |
| Malik Turner (WR) | Activated from the practice squad by the San Francisco 49ers. |
| Nick Zakelj (OG/C) | Activated from the practice squad by the San Francisco 49ers. |
| Trevis Gipson (DE/LB) | Signed by the San Francisco 49ers from the practice squad. |
October 17, 2025
| Marquez Valdes-Scantling (WR) | Calf injury, injured reserve. |
October 16, 2025
| George Kittle (TE) | Placed on the designated for return list by the San Francisco 49ers. |