1:50 PM - Isaac Guerendo (SF) had one carry for zero yards in Sunday's 23-20 win over Tampa Bay.

5:06 PM - Isaac Guerendo (SF) rushed five times for 22 yards and was not targeted as a receiver in Sunday's 24-23 loss to Arizona.

7:29 PM - Isaac Guerendo (SF) lost a fumble on his lone carry Sunday, failing to gain any yards while earning zero targets in a blowout win over the Patriots.

3:11 PM - Isaac Guerendo (SF) rushed five times for 19 yards in Sunday's 27-24 loss to the Rams.

5:20 PM - Isaac Guerendo (SF) (groin) suited up for Monday's season opener against the Jets but did not record a touch in the 32-19 win.

6:11 PM - Isaac Guerendo (SF) (groin) practiced in full Saturday and doesn't have an injury designation for Monday's Week 1 contest against the Jets.

6:44 PM - Isaac Guerendo (SF) (groin) remained limited in practice Friday, Nick Wagoner of ESPN.com reports.

4:57 PM - Isaac Guerendo (SF) (groin) is practicing on a limited basis Thursday, Cam Inman of The San Jose Mercury News reports.

5:18 PM - Isaac Guerendo (SF) tweaked his groin Monday and won't practice this week, Cam Inman of The San Jose Mercury News reports.

3:47 AM - Isaac Guerendo (SF) (hamstring) rushed 11 times for 32 yards and caught both of his targets for three yards in Friday's preseason tilt against Las Vegas.

3:11 PM - Isaac Guerendo (SF) (hamstring) will retake the practice field Tuesday, Nick Wagoner of ESPN.com reports.

1:40 PM - Isaac Guerendo (SF) Kyle Shanahan said Sunday he's "hopeful" Guerendo (hamstring) will be able to resume practicing this week and potentially play in Friday's preseason finale against the Raiders, Matt Barrows of The Athletic reports.

3:53 PM - Isaac Guerendo (SF) is expected to be sidelined multiple weeks due to the hamstring injury he sustained last week, Adam Schefter of ESPN reports.

3:19 PM - Isaac Guerendo (SF) (hamstring) departed Wednesday's training camp practice early, Jennifer Lee Chan of NBC Sports Bay Area reports.