San Francisco 49ers
| Week # | Date | Opponent | Results | Record | Streak | ||||
|---|---|---|---|---|---|---|---|---|---|
| 1 | Sunday, Sep. 10 |
@
Pit
|
W 30-7 | 1-0-0 | Won 1 | K.Pickett (232) | N.Harris (31) | A.Robinson (64) | Boxscore |
| 2 | Sunday, Sep. 17 |
@
LAR
|
W 30-23 | 2-0-0 | Won 2 | M.Stafford (307) | K.Williams (52) | P.Nacua (147) | Boxscore |
| 3 | Thursday, Sep. 21 |
vs
NYG
|
W 30-12 | 3-0-0 | Won 3 | B.Purdy (310) | C.McCaffrey (85) | D.Samuel (129) | Boxscore |
| 4 | Sunday, Oct. 1 |
vs
Ari
|
W 35-16 | 4-0-0 | Won 4 | B.Purdy (283) | C.McCaffrey (106) | B.Aiyuk (148) | Boxscore |
| 5 | Sunday, Oct. 8 |
vs
Dal
|
W 42-10 | 5-0-0 | Won 5 | B.Purdy (252) | J.Mason (69) | G.Kittle (67) | Boxscore |
| 6 | Sunday, Oct. 15 |
@
Cle
|
L 19-17 | 5-1-0 | Lost 1 | P.Walker (192) | J.Ford (84) | A.Cooper (108) | Boxscore |
| 7 | Monday, Oct. 23 |
@
Min
|
L 22-17 | 5-2-0 | Lost 2 | K.Cousins (378) | A.Mattison (39) | J.Addison (123) | Boxscore |
| 8 | Sunday, Oct. 29 |
vs
Cin
|
L 31-17 | 5-3-0 | Lost 3 | B.Purdy (365) | B.Purdy (57) | G.Kittle (149) | Boxscore |
| 10 | Sunday, Nov. 12 |
@
Jax
|
W 34-3 | 6-3-0 | Won 1 | T.Lawrence (185) | T.Etienne (35) | C.Kirk (104) | Boxscore |
| 11 | Sunday, Nov. 19 |
vs
TB
|
W 27-14 | 7-3-0 | Won 2 | B.Purdy (333) | C.McCaffrey (78) | B.Aiyuk (156) | Boxscore |
| 12 | Thursday, Nov. 23 |
@
Sea
|
W 31-13 | 8-3-0 | Won 3 | G.Smith (180) | Z.Charbonnet (47) | J.Smith-Njigba (41) | Boxscore |
| 13 | Sunday, Dec. 3 |
@
Phi
|
W 42-19 | 9-3-0 | Won 4 | J.Hurts (298) | J.Hurts (20) | A.Brown (114) | Boxscore |
| 14 | Sunday, Dec. 10 |
vs
Sea
|
W 28-16 | 10-3-0 | Won 5 | B.Purdy (368) | C.McCaffrey (145) | D.Samuel (149) | Boxscore |
| 15 | Sunday, Dec. 17 |
@
Ari
|
W 45-29 | 11-3-0 | Won 6 | K.Murray (211) | J.Conner (86) | T.McBride (102) | Boxscore |
| 16 | Monday, Dec. 25 |
vs
Bal
|
L 33-19 | 11-4-0 | Lost 1 | B.Purdy (255) | C.McCaffrey (103) | G.Kittle (126) | Boxscore |
| 17 | Sunday, Dec. 31 |
@
Wsh
|
W 27-10 | 12-4-0 | Won 1 | S.Howell (169) | B.Robinson (44) | T.McLaurin (61) | Boxscore |
| 18 | Sunday, Jan. 7 |
vs
LAR
|
L 21-20 | 12-5-0 | Lost 1 | S.Darnold (189) | E.Mitchell (52) | C.Conley (69) | Boxscore |
| 20 | Saturday, Jan. 20 |
vs
GB
|
W 24-21 | B.Purdy (252) | C.McCaffrey (98) | G.Kittle (81) | Boxscore | ||
| 21 | Sunday, Jan. 28 |
vs
Det
|
W 34-31 | B.Purdy (267) | C.McCaffrey (90) | D.Samuel (89) | Boxscore | ||
| 23 | Sunday, Feb. 11 |
@
KC
|
L 25-22 | P.Mahomes (333) | P.Mahomes (66) | T.Kelce (93) | Boxscore |