San Francisco 49ers
| Week # | Date | Opponent | Results | Record | Streak | Leaders (Pass Yds) | Leaders (Rush Yds) | Leaders(Rec Yds) | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Sunday, Sep. 11 |
@
Chicago
|
L 19-10 | 0-1-0 | Lost 1 | T.Lance (164) | T.Lance (54) | J.Jennings (62) | Boxscore |
| 2 | Sunday, Sep. 18 |
vs
Seattle
|
W 27-7 | 1-1-0 | Won 1 | J.Garoppolo (154) | J.Wilson (84) | B.Aiyuk (63) | Boxscore |
| 3 | Sunday, Sep. 25 |
@
Denver
|
L 11-10 | 1-2-0 | Lost 1 | J.Garoppolo (211) | J.Wilson (75) | D.Samuel (73) | Boxscore |
| 4 | Monday, Oct. 3 |
vs
LA Rams
|
W 24-9 | 2-2-0 | Won 1 | J.Garoppolo (239) | J.Wilson (74) | D.Samuel (115) | Boxscore |
| 5 | Sunday, Oct. 9 |
@
Carolina
|
W 37-15 | 3-2-0 | Won 2 | J.Garoppolo (253) | J.Wilson (120) | B.Aiyuk (58) | Boxscore |
| 6 | Sunday, Oct. 16 |
@
Atlanta
|
L 28-14 | 3-3-0 | Lost 1 | J.Garoppolo (296) | J.Wilson (25) | G.Kittle (83) | Boxscore |
| 7 | Sunday, Oct. 23 |
vs
Kansas City
|
L 44-23 | 3-4-0 | Lost 2 | J.Garoppolo (303) | J.Wilson (54) | G.Kittle (98) | Boxscore |
| 8 | Sunday, Oct. 30 |
@
LA Rams
|
W 31-14 | 4-4-0 | Won 1 | J.Garoppolo (235) | C.McCaffrey (94) | B.Aiyuk (81) | Boxscore |
| 10 | Sunday, Nov. 13 |
vs
LA Chargers
|
W 22-16 | 5-4-0 | Won 2 | J.Garoppolo (240) | E.Mitchell (89) | B.Aiyuk (84) | Boxscore |
| 11 | Monday, Nov. 21 |
@
Arizona
|
W 38-10 | 6-4-0 | Won 3 | J.Garoppolo (228) | E.Mitchell (59) | G.Kittle (84) | Boxscore |
| 12 | Sunday, Nov. 27 |
vs
New Orleans
|
W 13-0 | 7-4-0 | Won 4 | J.Garoppolo (222) | E.Mitchell (35) | B.Aiyuk (65) | Boxscore |
| 13 | Sunday, Dec. 4 |
vs
Miami
|
W 33-17 | 8-4-0 | Won 5 | B.Purdy (210) | C.McCaffrey (66) | C.McCaffrey (80) | Boxscore |
| 14 | Sunday, Dec. 11 |
vs
Tampa Bay
|
W 35-7 | 9-4-0 | Won 6 | B.Purdy (185) | C.McCaffrey (119) | B.Aiyuk (57) | Boxscore |
| 15 | Thursday, Dec. 15 |
@
Seattle
|
W 21-13 | 10-4-0 | Won 7 | B.Purdy (217) | C.McCaffrey (108) | G.Kittle (93) | Boxscore |
| 16 | Saturday, Dec. 24 |
vs
Washington
|
W 37-20 | 11-4-1 | Won 8 | B.Purdy (234) | R.McCloud (71) | G.Kittle (120) | Boxscore |
| 17 | Sunday, Jan. 1 |
@
Las Vegas
|
W 37-34 | 12-4-0 | Won 9 | B.Purdy (284) | C.McCaffrey (121) | B.Aiyuk (101) | Boxscore |
| 18 | Sunday, Jan. 8 |
vs
Arizona
|
W 38-13 | 13-4-0 | Won 10 | B.Purdy (178) | E.Mitchell (55) | B.Aiyuk (59) | Boxscore |
| 19 | Saturday, Jan. 14 |
vs
Seattle
|
W 41-23 | B.Purdy (332) | C.McCaffrey (119) | D.Samuel (133) | Boxscore | ||
| 20 | Sunday, Jan. 22 |
vs
Dallas
|
W 19-12 | B.Purdy (214) | E.Mitchell (51) | G.Kittle (95) | Boxscore | ||
| 21 | Sunday, Jan. 29 |
@
Philadelphia
|
L 31-7 | J.Johnson (74) | C.McCaffrey (84) | D.Samuel (33) | Boxscore |