3:33 PM - Brandon Aiyuk (SF) John Lynch said Monday that the 49ers are having "good talks" with Aiyuk, who hasn't been at the team facility for the offseason program, Matt Barrows of The Athletic reports.

12:51 PM - Brandon Aiyuk (SF) agent, Ryan Williams of Athletes First, denied reports on social media Sunday that the wide receiver has requested a trade from the 49ers, Mike Garafolo of NFL Network reports.

12:29 PM - Brandon Aiyuk (SF) John Lynch said Monday that the 49ers have not engaged in trade discussions regarding Aiyuk and that both sides continue to have active talks about a contract extension, Matt Maiocco of NBC Sports Bay Area reports.

4:02 PM - Brandon Aiyuk (SF) general manager John Lynch said Tuesday at the NFL Scouting Combine that the team wants to sign Aiyuk to a long-term contract extension, Eric Branch of the San Francisco Chronicle reports.

5:10 PM - Brandon Aiyuk (SF) recorded seven receptions on eight targets for 114 yards and a touchdown in Sunday's 27-10 win over the Commanders.

5:09 PM - Brandon Aiyuk (SF) caught four of 10 targets for 76 yards in Sunday's 19-17 loss to Cleveland.

8:35 PM - Brandon Aiyuk (SF) (shoulder) corralled all six of his targets for 148 yards in Sunday's 35-16 win over the Cardinals.

5:01 PM - Brandon Aiyuk (SF) (shoulder) doesn't have an injury designation for Sunday's game against the Cardinals, Matt Barrows of The Athletic reports.

7:15 PM - Brandon Aiyuk (SF) (shoulder) was a limited participant at Thursday's practice, Nick Wagoner of ESPN.com reports.

4:32 PM - Brandon Aiyuk (SF) (shoulder) wasn't wearing a non-contact jersey at the start of Thursday's practice, Cam Inman of The San Jose Mercury News reports.

4:01 PM - Brandon Aiyuk (SF) (shoulder) was a limited participant in practice Wednesday, Matt Barrows of The Athletic reports.

5:51 PM - Brandon Aiyuk (SF) (shoulder) was present for Monday's practice, Cam Inman of The San Jose Mercury News reports.

6:49 PM - Brandon Aiyuk (SF) (shoulder) is listed as inactive Thursday against the Giants, Lindsey Pallares of the 49ers' official site reports.

4:39 PM - Brandon Aiyuk (SF) (shoulder), who is listed as questionable for Thursday's game against the Giants, isn't expected to play, Adam Schefter of ESPN reports.

3:41 PM - Brandon Aiyuk (SF) (shoulder) is listed as questionable for Thursday's game against the Giants, Jennifer Lee Chan of NBC Sports Bay Area reports.

4:36 PM - Brandon Aiyuk (SF) Francisco head coach Kyle Shanahan said Aiyuk (shoulder) will be a limited participant in Tuesday's practice, Nick Wagoner of ESPN.com reports.

5:39 PM - Brandon Aiyuk (SF) (shoulder) was listed as a non-participant on Monday's practice estimation, Cam Inman of The San Jose Mercury News reports.

5:23 PM - Brandon Aiyuk (SF) caught all eight of his targets for 129 yards and two touchdowns in Sunday's 30-7 win over the Steelers.

3:03 AM - Brandon Aiyuk (SF) hauled in his lone target for 15 yards in Saturday's 21-20 preseason win over Denver.

6:28 PM - Brandon Aiyuk (SF) has been standing out early in San Francisco's offseason team activities, Jerry McDonald of The Mercury News reports.

7:07 PM - Brandon Aiyuk (SF) 49ers picked up the fifth-year option on Aiyuk's rookie contract Friday, Ian Rapoport of NFL Network reports.

1:14 PM - Brandon Aiyuk (SF) caught his lone target for 10 yards in Sunday's 31-7 NFC Championship Game loss to the Eagles.

9:21 PM - Brandon Aiyuk (SF) caught three of five targets for 73 yards in Saturday's 41-23 win over Seattle.

10:34 PM - Brandon Aiyuk (SF) had four receptions (five targets) for 59 yards in Sunday's 38-13 win over Arizona.

9:21 PM - Brandon Aiyuk (SF) had nine receptions (12 targets) for 101 yards and a touchdown while rushing once for 16 yards in Sunday's 37-34 win over the Raiders.

11:50 PM - Brandon Aiyuk (SF) hauled in five of seven targets for 81 yards in Saturday's 37-20 win over the Commanders.

8:35 PM - Brandon Aiyuk (SF) caught two of three targets for 57 yards and a touchdown in Sunday's 35-7 win over Tampa Bay.

8:35 PM - Brandon Aiyuk (SF) caught five of nine targets for 46 yards in Sunday's 33-17 win over the Dolphins.

10:10 PM - Brandon Aiyuk (SF) hauled in five of eight targets for 65 yards in Sunday's 13-0 win over New Orleans.

9:04 PM - Brandon Aiyuk (SF) corralled all six of his targets for 81 yards and a touchdown in Sunday's 31-14 win over the Rams.

11:20 PM - Brandon Aiyuk (SF) had seven receptions (11 targets) for 82 yards in Sunday's 44-23 loss to the Chiefs.

9:34 PM - Brandon Aiyuk (SF) corralled eight of 11 targets for 83 yards and two touchdowns in Sunday's 28-14 loss to the Falcons.

9:06 PM - Brandon Aiyuk (SF) caught three of four targets for 58 yards in Sunday's 37-15 win over the Panthers.

11:34 PM - Brandon Aiyuk (SF) caught all four of his targets for 37 yards in Monday's 24-9 win over the Rams.

9:01 PM - Brandon Aiyuk (SF) caught five of eight targets for 63 yards in Sunday's 27-7 win over the Seahawks.

1:15 PM - Brandon Aiyuk (SF) caught both of his targets for 40 yards and received one carry for seven yards in Sunday's 19-10 loss to the Bears.

1:15 PM - Brandon Aiyuk (SF) caught both of his targets for 40 yards and received one carry for seven yards in Sunday's 19-10 loss to the Bears.

11:38 PM - Brandon Aiyuk (SF) didn't catch his only target in Thursday's 17-0 loss to the Texans.

7:20 PM - Brandon Aiyuk (SF) is in uniform and appears set to play in Thursday's preseason game at Houston, Eric Branch of the San Francisco Chronicle reports.

6:14 PM - Brandon Aiyuk (SF) isn't expected to play in Saturday's preseason game against Minnesota, Cam Inman of The San Jose Mercury News reports.

8:28 PM - Brandon Aiyuk (SF) isn't slated to play in Friday's preseason game versus the Packers, Nick Wagoner of ESPN.com reports.

1:37 PM - Brandon Aiyuk (SF) has made a strong impression on teammates and reporters alike, with safety Jimmie Ward saying the wideout is "taking his game to another level" and ESPN's Nick Wagoner calling him "the team's most consistent offensive performer" at training camp.

1:37 PM - Brandon Aiyuk (SF) has made a strong impression on teammates and reporters alike, with safety Jimmie Ward saying the wideout is "taking his game to another level" and ESPN's Nick Wagoner calling him "the team's most consistent offensive performer" at training camp.

12:40 PM - Brandon Aiyuk (SF) has excelled in training camp for the 49ers, Jennifer Lee Chan of NBC Sports Bay Area reports.

12:40 PM - Brandon Aiyuk (SF) has excelled in training camp for the 49ers, Jennifer Lee Chan of NBC Sports Bay Area reports.

11:50 PM - Brandon Aiyuk (SF) hauled in four of eight targets for 69 yards in Sunday's 20-17 loss to the Rams.

10:22 PM - Brandon Aiyuk (SF) caught five of six targets for 66 yards in Sunday's 23-17 win over the Cowboys in the wild-card round.

10:44 PM - Brandon Aiyuk (SF) caught six of seven targets for 107 yards in Sunday's 27-24 win over the Rams.

9:15 PM - Brandon Aiyuk (SF) corralled four of six targets for 94 yards in Sunday's 23-7 win over the Texans.

9:59 PM - Brandon Aiyuk (SF) had one reception (two targets) for 36 yards in Sunday's 31-13 win over the Falcons.

10:54 PM - Brandon Aiyuk (SF) caught six of 11 targets for 62 yards and a touchdown in Sunday's 26-23 overtime win over the Bengals.

11:47 PM - Brandon Aiyuk (SF) caught three of six targets for 55 yards in Sunday's 30-23 loss to the Seahawks.

6:54 PM - Brandon Aiyuk (SF) should be key for the 49ers' passing game with fellow wide receiver Deebo Samuel (groin) ruled out for Sunday's contest in Seattle, Jerry McDonald of the Bay Area News Group reports.

11:16 PM - Brandon Aiyuk (SF) caught three of six targets for 91 yards in Sunday's 34-28 win over the Vikings.

4:44 PM - Brandon Aiyuk (SF) caught seven passes for 85 yards and one touchdown on seven targets against Jacksonville on Sunday.

11:39 PM - Brandon Aiyuk (SF) caught three of four targets for 26 yards in Monday night's 31-10 win over the Rams.

6:15 PM - Brandon Aiyuk (SF) had four receptions (seven targets) for 45 yards in Sunday's 33-22 win over the Bears.

4:28 PM - Brandon Aiyuk (SF) started and was on the field for 40 offensive snaps (71 percent), but only finished with one reception (one target) for six yards in Sunday's 30-18 loss to the Colts.

8:33 PM - Brandon Aiyuk (SF) caught two of four targets for 32 yards against Arizona on Sunday.

8:12 PM - Brandon Aiyuk (SF) caught one of three targets for a 15-yard reception against Seattle on Sunday.

5:45 PM - Brandon Aiyuk (SF) had one reception (two targets) for six yards in Sunday's 17-11 win over the Eagles.

4:11 PM - Brandon Aiyuk (SF) Kyle Shanahan said Aiyuk should see more playing time moving forward, as long as he stays healthy and regularly participates in practice, David Lombardi of The Athletic reports.

5:57 PM - Brandon Aiyuk (SF) (hamstring) -- who did not receive a target in Sunday's win over the Lions -- fell down the depth chart due to injury and not performance, David Lombardi of The Athletic reports.

6:45 PM - Brandon Aiyuk (SF) (hamstring) practiced fully Wednesday, Keiana Martin of the 49ers' official site reports.

2:36 PM - Brandon Aiyuk (SF) (hamstring) ran routes and caught passes during the part of Monday's practice open to the media, Nick Wagoner of ESPN.com reports.

3:04 PM - Brandon Aiyuk (SF) (hamstring) looked unencumbered while running sprints on a side field Thursday, and he's on track to be a full-go Week 1 at Detroit, Michael-Shawn Dugar of The Athletic reports.

6:43 PM - Brandon Aiyuk (SF) (hamstring) didn't take part of the part of Wednesday's practice open to the media, Nick Wagoner of ESPN.com reports.

4:52 PM - Brandon Aiyuk (SF) is dealing with what's being described as a slight hamstring issue, Nick Wagoner of ESPN.com reports.

11:25 PM - Brandon Aiyuk (SF) caught one of three targets for three yards in Sunday's 15-10 preseason win over the Chargers.

3:37 PM - Brandon Aiyuk (SF) did not take part in Wednesday's OTA due to a minor groin injury, Matt Barrows of The Athletic reports.

5:47 PM - Brandon Aiyuk (SF) who suffered a high-ankle sprain in this past Saturday's win over the Cardinals, won't play in Sunday's season finale against the Seahawks, Nick Wagoner of ESPN.com reports.

8:38 PM - Brandon Aiyuk (SF) recorded one reception on two targets for 15 yards in Week 16 against the Cardinals. He added one rushing attempt for 16 yards.

5:15 PM - Brandon Aiyuk (SF) caught nine of 13 targets for 73 yards and a touchdown during Sunday's 41-33 loss to the Cowboys.

8:55 PM - Brandon Aiyuk (SF) caught 10 of 16 targets for 119 yards during Sunday's 23-15 loss to Washington.

11:41 PM - Brandon Aiyuk (SF) secured five of nine targets for 95 yards and a touchdown while also returning one punt for 16 yards in the 49ers' 34-24 loss to the Bills on Monday night.

6:37 PM - Brandon Aiyuk (SF) a positive COVID-19 test on Nov. 20, Samuel told Cam Inman of The San Jose Mercury News on Friday that he's "feeling fresh physically and mentally" in advance of Sunday's game against the Bills.

4:55 PM - Brandon Aiyuk (SF) 49ers activated Aiyuk (undisclosed) from the reserve/COVID-19 list Wednesday.

1:08 PM - Brandon Aiyuk (SF) 49ers are expected to activated Aiyuk (undisclosed) from the reserve/COVID-19 list Tuesday, Chris Biderman of Sacramento Bee reports.

7:37 PM - Brandon Aiyuk (SF) won't be activated from the reserve/COVID-19 list for Sunday's game against the Rams, Jennifer Lee Chan of NBC Sports Bay Area reports.

5:05 PM - Brandon Aiyuk (SF) Kyle Shanahan said Friday that he hasn't heard anything about Aiyuk (reserve/COVID-19) potentially being able to play in Sunday's game against the Rams, Matt Maiocco of NBC Sports Bay Area reports.

4:39 PM - Brandon Aiyuk (SF) 49ers placed Aiyuk on the reserve/COVID-19 list Friday, Matt Maiocco of NBC Sports Bay Area reports.

8:44 PM - Brandon Aiyuk (SF) caught seven of 14 targets for 75 yards and a touchdown while losing eight yards on his only rushing attempt during Sunday's 27-13 loss to the Saints.

4:56 PM - Brandon Aiyuk (SF) brought in five of eight targets for 70 yards and rushed three times for 31 yards and a touchdown in the 49ers' 36-9 win over the Giants on Sunday.

4:35 PM - Brandon Aiyuk (SF) caught two of three targets for 21 yards in Sunday's 31-13 win over the Jets.

7:54 PM - Brandon Aiyuk (SF) (hamstring) wasn't listed on the 49ers' injury report Wednesday.

3:02 PM - Brandon Aiyuk (SF) (hamstring) is listed as inactive Sunday versus the Cardinals, Nick Wagoner of ESPN.com reports.

5:57 PM - Brandon Aiyuk (SF) (hamstring) was limited in practice Thursday, Nick Wagoner of ESPN.com reports.

6:47 PM - Brandon Aiyuk (SF) (hamstring) didn't practice Wednesday, David Lombardi of The Athletic reports.

3:39 PM - Brandon Aiyuk (SF) Kyle Shanahan said Wednesday that Aiyuk (hamstring) isn't expected to practice but has "a chance," David Lombardi of The Athletic reports.

4:38 AM - Brandon Aiyuk (SF) (hamstring) did not participate in Monday's team practice, Nick Wagoner of ESPN.com reports.

11:34 PM - Brandon Aiyuk (SF) coach Kyle Shanahan said that he is hopeful Aiyuk (hamstring) can return to practice next week, Jennifer Lee Chan of NBC Sports Bay Area reports.

3:53 PM - Brandon Aiyuk (SF) Kyle Shanahan called Aiyuk "week-to-week" due to a mild left hamstring strain, Nick Wagoner of ESPN.com reports.

3:23 PM - Brandon Aiyuk (SF) (hamstring) was unable to finish practice Sunday after he "appeared to come up lame after a deep route," per Jennifer Lee Chan of NBC Sports Bay Area.

4:32 PM - Brandon Aiyuk (SF) has signed a four-year, 12.5 million contract with the 49ers, Matt Maiocco of NBC Sports Bay Area reports.

12:10 PM - Brandon Aiyuk (SF) (abdomen) has been medically cleared, Eric Branch of the San Francisco Chronicle reports.

6:35 AM - Brandon Aiyuk (SF) will have to compete for a significant role on offense during training camp, Matt Maiocco of NBC Sports Bay Area reports.

11:20 PM - Brandon Aiyuk (SF) 49ers selected Aiyuk in the first round of the 2020 NFL Draft, 25th overall.