April 7, 2025
| Joel Nystrom (D) | Assigned to the Chicago Wolves (AHL). |
| Trent Frederic (W/C) | Ankle injury, day-to-day. |
| Drew Doughty (D) | Ankle injury, day-to-day. |
| Joel Edmundson (D) | Upper body injury, day-to-day. |
| K'Andre Miller (D) | Illness, day-to-day. |
| Matt Rempe (RW/C) | Missed 4 games (upper body injury). |
| Olle Lycksell (LW/RW) | Placed on waivers by the Philadelphia Flyers. |
| Jimmy Schuldt (D) | Assigned to the San Jose Barracuda (AHL). |
| Jimmy Schuldt (D) | Missed 4 games (lower body injury). |
| Quentin Musty (LW) | Assigned to the San Jose Barracuda (AHL). |
| Shakir Mukhamadullin (D) | Upper body injury, remainder of the regular season. |
| Tyler Toffoli (LW/RW) | Lower body injury, day-to-day. |
| Andrei Loshko (RW) | Signed by the Seattle Kraken to a three-year entry-level contract. |
| Jani Nyman (LW/RW) | Assigned to the Coachella Valley Firebirds (AHL). |
| Ryker Evans (D) | Illness, day-to-day. |
| Kailer Yamamoto (W/C) | Recalled from the Tucson Roadrunners (AHL). |
| Colin Miller (D) | Illness, day-to-day. |
| Kieron Walton (C/LW) | Signed by the Winnipeg Jets to a three-year entry-level contract. |
April 6, 2025
| Justin Robidas (C) | Assigned to the Chicago Wolves (AHL). |
| Jamie Benn (LW/C) | Missed 2 games (lower body injury). |
| Jesse Puljujarvi (RW/LW) | Recalled from the Charlotte Checkers (AHL). |
| Matt Kiersted (D) | Recalled from the Charlotte Checkers (AHL). |
| Rasmus Asplund (RW/C) | Recalled from the Charlotte Checkers (AHL). |
| Carter George (G) | Assigned to the Ontario Reign (AHL). |
| Jake Middleton (D) | Upper body injury, day-to-day. |
| David Savard (D) | Undisclosed, day-to-day. |
| Emil Heineman (LW/RW) | Undisclosed, day-to-day. |
| Josh Anderson (LW/RW) | Missed 1 game (personal reasons). |
| Spencer Stastney (D) | Missed 1 game (upper body injury). |
| Joona Koppanen (LW/C) | Recalled from the Wilkes-Barre/Scranton Penguins (AHL). |
| Philip Tomasino (RW/LW) | Upper body injury, day-to-day. |
| Dalibor Dvorsky (C) | Recalled from the Springfield Thunderbirds (AHL). |
| Kailer Yamamoto (W/C) | Assigned to the Tucson Roadrunners (AHL). |
| Nils Hoglander (LW/RW) | Missed 6 games (undisclosed). |
| Aliaksei Protas (LW/RW) | Foot injury, week-to-week. |
| Ludwig Persson (C/LW) | Assigned to the Hershey Bears (AHL). |
April 5, 2025
| Jacob Trouba (D) | Lower body injury, day-to-day. |
| John Gibson (G) | Lower body injury, day-to-day. |
| Fraser Minten (C) | Recalled from the Providence Bruins (AHL). |
| Jeffrey Viel (LW) | Assigned to the Providence Bruins (AHL). |
| Jordan Greenway (LW/C) | Lower body injury, sidelined indefinitely. |
| Kevin Mandolese (G) | Assigned to the Colorado Eagles (AHL). |
| Nathaniel Day (G) | Signed by the Edmonton Oilers to a three-year entry-level contract. |
| Trent Frederic (W/C) | Missed 18 games (lower body injury). |
| Cameron Crotty (D) | Recalled from the Iowa Wild (AHL). |
| Josh Anderson (LW/RW) | Personal reasons, day-to-day. |
| Ozzy Wiesblatt (RW/LW) | Assigned to the Milwaukee Admirals (AHL). |
| Evgeni Malkin (C/LW) | Missed 4 games (upper body injury). |
| Joona Koppanen (LW/C) | Assigned to the Wilkes-Barre/Scranton Penguins (AHL). |
| Alexandar Georgiev (G) | Missed 1 game (upper body injury). |
| Eeli Tolvanen (LW/RW) | Missed 1 game (undisclosed). |
| Jaden Schwartz (LW) | Missed 1 game (undisclosed). |
| Max Sasson (W/C) | Recalled from the Abbotsford Canucks (AHL). |
| Nikolaj Ehlers (LW/RW) | Foot injury, day-to-day. |
April 4, 2025
| Ville Husso (G) | Recalled from the San Diego Gulls (AHL). |
| Noah Ostlund (C/LW) | Recalled from the Rochester Americans (AHL). |
| Tyson Kozak (C/LW) | Hip flexor strain, week-to-week. |
| Andrei Svechnikov (RW/LW) | Undisclosed, week-to-week. |
| Dominik Shine (RW/LW) | Assigned to the Grand Rapids Griffins (AHL). |
| Elmer Soderblom (LW/RW) | Missed 4 games (undisclosed). |
| Leon Draisaitl (C/W) | Undisclosed, day-to-day. |
| Jacob Fowler (G) | Assigned to the Laval Rocket (AHL). |
| Jacob Fowler (G) | Signed by the Montreal Canadiens to a three-year entry-level contract. |
| Magnus Chrona (G) | Signed by the Nashville Predators to a one-year two-way contract extension. |
| Gabriel Carriere (G) | Assigned to the San Jose Barracuda (AHL). |
| Alexandre Texier (LW/RW) | Upper body injury, day-to-day. |
| Dylan Holloway (W/C) | Lower body injury, week-to-week. |
| David Kampf (C) | Upper body injury, day-to-day. |
| Jake McCabe (D) | Undisclosed, day-to-day. |
| Nils Aman (C/W) | Undisclosed, day-to-day. |
| Tyler Myers (D) | Undisclosed, day-to-day. |
| Hunter Shepard (G) | Recalled from the Hershey Bears (AHL). |
| Logan Thompson (G) | Upper body injury, sidelined indefinitely. |
| Matt Roy (D) | Missed 2 games (personal reasons). |
April 3, 2025
| Dalton Bancroft (RW) | Signed as an undrafted free agent by the Boston Bruins to a one-year entry-level contract. |
| Justin Robidas (C) | Recalled from the Chicago Wolves (AHL). |
| Jonathan Drouin (RW/LW) | Lower body injury, day-to-day. |
| Martin Necas (RW) | Upper body injury, day-to-day. |
| Jamie Benn (LW/C) | Lower body injury, day-to-day. |
| Sam Steel (C/LW) | Missed 1 game (undisclosed). |
| Austin Watson (RW/LW) | Assigned to the Grand Rapids Griffins (AHL). |
| Anton Lundmark (RW/LW) | Signed by the Florida Panthers to a one-year entry-level contract. |
| Kenny Connors (C) | Signed by the Los Angeles Kings to a two-year entry-level contract. |
| Ozzy Wiesblatt (RW/LW) | Recalled from the Milwaukee Admirals (AHL). |
| Spencer Stastney (D) | Upper body injury, day-to-day. |
| Anthony Duclair (RW/LW) | Personal reasons, sidelined indefinitely. |
| Emil Bemstrom (RW/LW) | Assigned to the Wilkes-Barre/Scranton Penguins (AHL). |
| Alexandar Georgiev (G) | Upper body injury, day-to-day. |
| Gabriel Carriere (G) | Recalled from the San Jose Barracuda (AHL). |
| Henry Thrun (D) | Missed 9 games (upper body injury). |
| Shakir Mukhamadullin (D) | Upper body injury, day-to-day. |
| Ryan Winterton (C/W) | Assigned to the Coachella Valley Firebirds (AHL). |
| Luke Glendening (C/RW) | Missed 1 game (personal reasons). |
| Olli Maatta (D) | Missed 2 games (lower body injury). |
| Alex Pietrangelo (D) | Missed 4 games (lower body injury). |
| Luke Schenn (D) | Missed 1 game (undisclosed). |
